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线性丙烯酰胺,英文名称Linear Acrylamide(Linear Polyacrylamide,简称LPA),是一种共沉淀剂,有助于核酸纯化过程中核酸的沉淀。 本质上讲,该丙烯酰胺是一种中性载体,且非生物性来源,因此,不含潜在的核酸或核酸酶污染。

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Why do we use linear polyacrylamide?

The use of linear polyacrylamide eliminates the risk of trace contaminants possibly introduced during the precipitation step. Co-precipitation of DNA or RNA with linear polyacrylamide allow precipitation of picogram amounts of nucleic acids.

What is polyacrylamide used for?

Polyacrylamides are water-soluble synthetic linear polymers made of acrylamide or the combination of acrylamide and acrylic acid. Polyacrylamide finds applications in pulp and paper production, agriculture, food processing, mining, and as a flocculant in wastewater treatment.

What is Linear Polyacrylamide (LPA)?

Linear polyacrylamide (LPA) is a material used in a variety of capillary gel electrophoresis applications and some coated capillaries. It is susceptible to degradation when exposed to high intensity light sources at low UV wavelengths.

What is linear acrylamide?

Chemically synthesized linear acrylamide, free of nuclease contamination, eliminates the risk of trace contamination introduced by the precipitation process. Polyacrylamides exhibit strong hydrogen bonding and water solubility resulting in a variety of uses in diverse industries.

Can linear polyacrylamide be used as a carrier molecule during alcoholic precipitation?

Linear polyacrylamide can be used as a carrier molecule during alcoholic precipitation. Adding linear polyacrylamide as a neutral carrier to ethanol precipitations is more advantage than using other precipitation methods such as using glycogen or yeast RNA.

Why is poly(acrylamide) a good soluble polymer?

The thermal stability of poly (acrylamide) solutions are generally higher than most other water-soluble polymers; however, the high molecular weight species, like their POE equivalents, have very high extensional viscosities, favor-able for good drag reduction behavior, but this also reflects on their rapid degradation under mechanical deformation.