Is polyacrylamide an ultralow fouling surface coating?

In this work, polyacrylamide is investigated as an ultralow fouling surface coating to highly resist protein adsorption, cell adhesion, and bacterial attachment. Polyacrylamide was grafted on gold surfaces via surface-initiated atom transfer radical polymerization (ATRP).

Is polyacrylamide a good antifouling material?

Strong hydrogen bond with water is considered the key attribute for the ultralow fouling properties of polyacrylamide. This is the first work to graft gold surfaces with polyacrylamide brushes via ATRP to achieve ultralow fouling surfaces, demonstrating that polyacrylamide is a promising alternative to traditional PEG-based antifouling materials.

Is polyacrylamide a biofouling polymer?

Polyacrylamide has actually been shown to be an ultralow biofouling polymer that is highly resistant to protein adsorption . Similar phenomena, i.e. polymers with amide groups have better protein repellency than those with ester groups, have also been reported by others.

What is the difference between poegma and polyacrylamide?

Polyacrylamide exhibited serum adsorption of 2.8 ng cm −2 and plasma adsorption of 1.7 ng cm −2 at the optimal film thickness of 39.2 nm , whereas pOEGMA showed serum and plasma adsorption of 30 and 10 ng cm −2, respectively, with 20–25 nm thick polymer brushes .

Which polymers have the best biofouling properties?

Recently, zwitterionic poly (carboxybetaine) and poly (sulfobetaine) as well as equimolarily mixed positively and negatively charged polymers have drawn the most attention due to their ultralow biofouling properties , , .

Which antifouling zwitterionic polymers are derived from natural amino acids?

We developed and investigated two new antifouling zwitterionic polymers, poly (lysine methacrylamide) (pLysAA) and poly (ornithine methacrylamide) (pOrnAA), both derived from natural amino acids – lysine and ornithine, respectively.