How often should you use c11-13 isoparaffin & c13-14 isododecane?

Daily or occasional use may extend over many years. C11-13 Isoparaffin, C13-14 Isoparaffin, and isododecane are used in hair sprays, and effects on the lungs that may be induced by aerosolized products containing these ingredients are of concern.

Is c10-12 isoparaffin toxic?

Subchronic inhalation exposure to C10-11 isoparaffin at concentrations up to 900 ppm and to C10-12 isoparaffin at concentrations up to 1444 ppm did not induce significant toxic effects, other than mild structural changes in the kidneys of male, but not female, rats. Low-grade anemia was also observed in male rats exposed to C10-12 isoparaffin.

What is the highest concentration of isoparaffin & isododecane?

The results of a Personal Care Products industry survey indicate that ingredient use concentrations have ranged from (lowest to highest) 0.0001% (C13-14 Isoparaffin) to 90% (Isododecane).

Does c10-12 isoparaffin cause anemia?

Low-grade anemia was also observed in male rats exposed to C10-12 isoparaffin. Inhalation exposure to isooctane (up to 1180 ppm) in rats for 12 weeks did not cause death; however a treatment-related increase in kidney weight was observed.

Are c11-13 isoparaffin & c13-14 isododecane harmful to the lungs?

C11-13 Isoparaffin, C13-14 Isoparaffin, and isododecane are used in hair sprays, and effects on the lungs that may be induced by aerosolized products containing these ingredients are of concern. The aerosol properties that determine deposition in the respiratory system are particle size and density.

Do C10-11 and c12-15 isoparaffins induce phtotoxicity or photosensitization in human?

C10-11, C11-13, and C12-15 isoparaffins did not induce sensitization, phototoxicity, or photosensitization in in human patch tests. Skin sensitization, phtotoxicity, and photosensitization tests on Isopar® G, Isopar® L, and Isopar® M were conducted using panels consisting of more than 100 subjects.